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Do not use this medication without telling your doctor if you are breast-feeding a baby. Lorazepam is sometimes used as an alternative to haloperidol when there is the need for rapid sedation of violent or agitated individuals, but haloperidol plus promethazine is preferred due to better effectiveness and due to lorazepam's adverse effects on respiratory function. This contrasts with the highly lipid-soluble diazepam, which, although rapidly absorbed orally or rectally, soon redistributes from the serum to other parts of the body, in particular body fat. * Paradoxical effects: In some cases, there can be paradoxical effects with benzodiazepines, such as increased hostility, aggression, angry outbursts, and psychomotor agitation. Lorazepam tablets of the Ativan brand also contain lactose, microcrystalline cellulose, polacrilin, magnesium stearate, and colouring agents (indigo carmine—E132—in blue tablets and tartrazine—E102— in yellow tablets). What happens if I miss a dose?Take the missed dose as soon as you remember. On regular administration, maximum lorazepam serum levels are attained after three days. Keep track of how many pills have been used from each new bottle of this medicine. Among benzodiazepines, lorazepam has a relatively high addictive potential. This metabolism does not involve hepatic oxidation and, therefore, is relatively unaffected by reduced liver function.