The anterograde amnesia and sedative-hypnotic effects of benzodiazepines such as lorazepam are sometimes used by predators on unwitting victims as date rape drugs, or for the purpose of robbery; however, alcohol is the most common drug involved in such crimes.

An example would be the inappropriate use to relieve anxiety associated with acute severe asthma. In this category, benzodiazepines are most commonly used. On regular administration, maximum lorazepam serum levels are attained after three days. Withdrawal symptoms can range from anxiety and insomnia to seizures and psychosis. Additionally the elderly tend to take more drugs which may interact or enhance the effects of benzodiazepines. After its introduction in 1977, lorazepam's principal use was in treating anxiety. Do not miss any scheduled visits to your doctor. Lorazepam is considered to be a short-acting drug which, similar to other benzodiazepines, exerts its therapeutic as well as adverse effects via its interaction at benzodiazepine binding sites, which are located on GABAA receptors in the central nervous system. Ativan should never be shared with another person, especially someone who has a history of drug abuse or addiction. Rebound effects often resemble the condition being treated but typically at a more intense level and may be difficult to diagnose.