The solvents used are polyethylene glycol 400 and propylene glycol.

However, if mechanical ventilation becomes necessary, lorazepam may be used to facilitate deep sedation. Lorazepam injectable solution is administered either by deep intramuscular injection or by intravenous injection. Lorazepam is considered to be a short-acting drug which, similar to other benzodiazepines, exerts its therapeutic as well as adverse effects via its interaction at benzodiazepine binding sites, which are located on GABAA receptors in the central nervous system. Do not use Ativan if you are pregnant. It is not known whether Ativan passes into breast milk or if it could harm a nursing baby. Tell your doctor if you regularly use any of these other medicines. It is dangerous to try and purchase Ativan on the Internet or from vendors outside of the United States. It may further reduce the patient's ability to protect his or her airway during sleep. Longer-term use, up to six months, does not result in further accumulation. However, adverse effects such as behavioural disinhibition may make benzodiazepines inappropriate for some acutely psychotic patients.